Effects of early postburn escharectomy on the permeability of cadiac and pulmonary blood vessels in rats
- VernacularTitle:烧伤早期切痂对大鼠心肺血管通透性影响
- Author:
Zhiqing LI
;
Zongcheng YANG
;
Jiahan WAN
;
Yuesheng HUANG
- Publication Type:Journal Article
- From:Journal of Third Military Medical University
2001;23(4):393-394
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the prophylactic-therapeutic role of escharectomy during early postburn stage on internal organ dysfunction. Methods A total of 72 Wistar rats were randomized into 3 groups: burn without escharectomy group (A group), burn with escharectomy during early postburn stage (B group) and normal control. Vascular permeability were measured with 99Tc-labelled albumin. Furthermore, the effect of burn sera on permeability of monolayer of vascular endothelial cell (EC) was observed. Results Vascular permeability in group B was significantly lower than in group A. When exposed to burn sera, EC monolayer permeability in group B is decreased when compared with group A. Conclusion Escharectomy during early postburn stage could restore endothelial permeability
