Study on changes of ROS, GSH content, and GSH - PX activity of serum in persons under different state of exercise

VernacularTitle:不同运动状态下人血清中活性氧及其清除体系中某些因素的变化
Author: Hongzhen LIU ; Yongqiang LENG
Publication Type:Journal Article
From: Chinese Journal of Tissue Engineering Research 2001;5(5):57-58
CountryChina
Language:Chinese
Abstract: ObjectiveTo probe the alterated characteristic of reactive oxygen species, reduce glutathione and glutathione peroxidase (GSH - PX) in serum of persons. Method Under the controlled load by treadmill, correlative indexes were determined during resting state, sub - maximalload and exhaustive exercise. ResultROS level of serum increased significantly during sub- maximal load compaired with that of restingstate. The ROS level during exhaustive exercise was higher than that of sub - maximal load( P ＜0. 01 ) . GSH content and GSH - PX activity de-creased significantly( P ＜0. 001 ). GSH content and GSH - PX reactivity decreased significantly( P ＜0. 001 ) during sub - maxiaml load and in-creased after exhaustive exercise which was still lower that of resting state. Conclusion ROS increased with the enhancement of exercise intensityand the time. GSH and GSH - PX showed a significant decrease in content and activity respectively followed by apparent enhancement.