Influence of Nao-xue-bao on blood coagulation and platelet aggregation in rats
- VernacularTitle:中药脑血宝制剂对凝血和血小板聚集率的影响
- Author:
Kun HUA
;
Tianshu LI
;
Ling GAO
;
Shigong ZHU
- Publication Type:Journal Article
- From:
Chinese Journal of Pathophysiology
2001;17(5):455-457
- CountryChina
- Language:Chinese
-
Abstract:
AIM and METHODS:To study the effect of Nao-xue-bao at three different doses on blood coagulation，platelet aggregation by observing the changes in activated partial thromboplastin time (APTT), prothrombin time (PT), antithrombin-Ⅲ(AT-III), fibrinogen(Fng), plasminogen(Plg) and platelet aggregation(PAG). RESULTS:Compared with thrombosis group, the rats treated with Naoxuebao showed that the plasma APTT,PT were longer, and the activity of AT-III was increased. The content of Fng was reduced, TT was longer, there was a negative correlation between Fng and TT. Furthermore PAG-1, PAG-5 and PAG-M were reduced. CONCLUSION:Nao-xue-bao could inhibit thrombosis in different keys of blood coagulation.
