The change of calcitonin gene-related peptide immunoreactive nerve fibers in acute inflammatory pulpitis in rats
- VernacularTitle:大鼠急性牙髓炎症降钙素基因相关肽免疫反应性神经纤维的变化
- Author:
Zhizhong CAO
;
Jun LIU
;
Zhonghua ZHOU
;
Hui YE
;
Weizhong TANG
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
2001;22(5):459-460
- CountryChina
- Language:Chinese
-
Abstract:
Objective：To investigate the changes of calcitonin gene-related peptide immunoreactive (CGRP-IR)nerve fibers in rat dental pulps during acute inflammation. Methods： Rat acute pulpitis model was established by silk thread ligation and the change of CGRP-IR nerve fibers was observed with immunohistochemical method.Results： In radical pulp,the CGRP-IR nerve fibers became denser and more heavily stained；in the coronal pulp,the number of CGRP-IR nerve fibers decreased,but the background staining was heavier. Conclusion： During acute inflammation,the amount of CGRP increases in dental pulps, and is released into the surronding tissue in a large scale in the coronal region.
