Cost-effectiveness Analysis of the Antibiotic Application in 230 Patients Undergoing Laparoscopic Cholecystectomy
- VernacularTitle:230例经腹腔镜胆囊切除术患者应用抗生素的成本-效果分析
- Author:
Xiaocong ZUO
;
Shikun LIU
;
Bingling XIE
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(6):344-346
- CountryChina
- Language:Chinese
-
Abstract:
To explore the rational use of antibiotics in patients undergoing laparoscopic cholecystectomy(LC).METHODS： The antibiotic use in the selected operation patients was retrospectively studied.230 patients were divided into four groups.A group： Perioperative administration of drug； B group： Preoperative administration for 3 to 7 days and perioperative administration； C group： Perioperative administration and postoperative administration for 2 to 7 days； D group： Preoperative administration for 2 to 7 days， perioperative administration and postoperative administration for 2 to 7 days.Four groups were compared about the efficacy， length of hospital stay and hospitalization expenses.RESULTS： There were no significant differences in efficacy among A， B， C， D and in average length of hospital stay and hospitalization expenses between A and D groups.A group was the lowest in two indices and had the best cost-effectiveness ratio.CONCLUSION： There is clinical significance of preventive antibiotic application in LC patients； perioperative use is the best choice； Cefazolin is the first choice.
