Determination of Ribavirin in Ribavirin Eye Drops
- VernacularTitle:RP-HPLC法测定利巴韦林滴眼液中利巴韦林的含量
- Author:
Fang LIU
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(6):268-369
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： A RP-HPLC method for determination of ribavirin in ribavirin eye drops was developed.METHODS： In the method,μ Bondapak C18 ODS was used as the stationary phase and water as the mobile phase with the detection wavelength at 207nm.RESULTS： The linear range of ribavirin was 12.5～100.0μ g/ml(r=0.9 994,n=5).The average recovery rate was 98.47％ ,RSD=0.92％ (n=5).CONCLUSION： This method is accurate,rapid and simple for the determination of ribavirin in ribavirin eye drops.
