Management of Parkinson's Diseases with Microelectrode-guided Stereotactic Pallidotomy and Thalamotomy
- VernacularTitle:微电极引导立体定向手术治疗帕金森病的研究
- Author:
Gaoyu CUI
;
Hua FENG
;
Xianrong WANG
;
Guocai WU
;
Zhi CHEN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2001;5(10):154-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the methods and outcome of 71 patients with Parkinson's disease treated with microelectrode-guided stereotactic pallidotomy and thalamotomy. Method Pallidal and thalamal target sites are chosen by supervision of microelectrode recording technique in 71 patients with Parkinson's disease. The UPDRS motor score was used to evaluate the outcomes 12 weeks before and after operation Result After 12 months follow-up, tremor disappeared completely or nearly completely in 12 patients who underwent unilateral and l bilateral ventrolateral thalamotomy. Dramatic improvement of tremor, rigidity, bradykinesia were observed in 57 patients underwent posteroventral pallidotomy,including 6 underwent bilateral posteroventral pallidotomy. Intracerebral hemorrhage was observed in l patient. Conclusion Microelectrode-guided stereotactic pallidotomy and thalamotomy are effective in treatmenting Parkinson's disease, but with serious complications
