Expression of ATP synthase 6 in breast cancer cell line, T47D cells, induced by heregulin β1
- Author:
Yanbo SUN
;
Guizhen YANG
- Publication Type:Journal Article
- Keywords:
heregulin;
breast cancer cells;
ATP synthase 6
- From:
Journal of Jilin University(Medicine Edition)
2002;28(2):111-114
- CountryChina
- Language:Chinese
-
Abstract:
Objective : To explore expression of related genes in breast cell line T47D induced by heregulin β1. Methods: Suppression subtractive hybridization was performed using cDNA sub traction kit to detect expression of heregulin-responsive genes in T47D cells. Results: ATP syn thase 6 was up-regulated by heregulin β1 in T47D cells at 1 and 6 hours. Conclusion: Heregulin β1 participates in the regulation of expression of both ATP synthase 6 and oxidative phosphoryla tion of T47D cells.
