Anticancer Agents from Endophytic Fungi
- VernacularTitle:植物内生真菌抗肿瘤药物研究进展
- Author:
Min QIU
;
Ruisheng XIE
;
Yu SHI
;
Haimin CHEN
- Publication Type:Journal Article
- Keywords:
Endophytic fungi;
Bioactivity;
Anticancer
- From:
China Biotechnology
2009;29(1):93-104
- CountryChina
- Language:Chinese
-
Abstract:
Various cancers have seriously threatened human' s health. Screening newer and more effective anticancer agents from natural sources to cure these diseases is the focus in research. As novel sources of potential medicine, a number of metabolites isolated from endophytic fungi have been proved to have anticancer bioactivity. Usually, these endophytic fungi have special biochemical pathway and they can accumulate anticancer agents in cultures such as taxane, alkaloids, cytochalasins, podophyllotoxin, brefeldin A and so forth. The research advance on anticancer agents purified from endophytic fungi is expatiated systemically. In addition, the strategy of screening anticancer agents as well as the prospect on this area is introduced briefly.
