The biological characteristics of p300/CBP-associated factor and relationship with disease
10.3760/cma.j.issn.1673-4408.2011.02.014
- VernacularTitle:p300/CBP相关因子的生物特性及其与疾病的关系
- Author:
Jingyun XIE
- Publication Type:Journal Article
- Keywords:
p300/CBP-associated factor;
Histone acetyltransferases;
Histone modification
- From:International Journal of Pediatrics
2011;38(2):139-141
- CountryChina
- Language:Chinese
-
Abstract:
p300/CBP-associated factor (PCAF)is an important histone acetyltransferase in eukaryotic cells. PCAF can acetylizes histone and non-histone. PCAF participates in various biological processes of cells and in the interaction between virus and cells. The imbalance of PCAF would lead to abnormal development of various organs, and related to the development of some tumors.
