The study on change of serum cytokines levels and its correlation with function rehabilitation in patients with cerebral infarction
- VernacularTitle:脑梗死患者血清细胞因子水平与功能恢复的相关性研究
- Author:
Zuoxiao LI
;
Xiu CHEN
;
Hua TAN
;
Xianji XIONG
;
Jianyi PENG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2001;5(21):150-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the pathogenetic role and clinical significance of interleukin 6(IL－ 6 ),tumor necrosis factor(TNF) and soluble interleukin－ 2 receptor(sIL－ 2R) in patients with cerebral infarction(CI) .Methods The IL－ 6,TNF and sIL－ 2R levels were measured in 46 CI patients with ELISA. Results The serum IL－ 6,TNF and sIL－ 2R levels of CI group were much higher than those of controls group .The variation of IL－ 6,TNF and sIL－ 2R levels was closely related to the size of cerebral infarction. The serum IL－ 6,TNF and sIL－ 2R levels of recovery period were much lower than those of acute period in patients with CI .Conclusions The IL－ 6 ,TNF and sIL－ 2R take part in the pathologic process after CI .The measurement of IL－ 6, TNF and sIL－ 2R is useful in determining the size of cerebral infarction.
