The relation between prognosis and nocturnal blood pressure variation in hypertensive patients with lacunar infarct
- VernacularTitle:夜间血液变化与高血压腔隙性脑梗死发后及预后的相关性分析
- Author:
Weiwei ZHANG
;
Yonghua HUANG
;
Juan LI
;
Jun FENG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2001;5(19):146-147
- CountryChina
- Language:Chinese
-
Abstract:
Objective We conducted a study using MRI and ambulatory blood pressure monitoring(ABPM) to determine whether an inapporpriately low nocturnal blood pressure,or an excess fall in nocturnal blood pressure,might be responsible for lacunar infarct.Method ABPM and Casul blood pressure(CBP) were examined in 35 hypertentives with lacunar infarct( LI) and 33 hypertentives without lacunar infarct as control group.Results There is no significant difference of CBP between two groups.But the mean nighttime systolic blood pressure(nSBP) and diastolic blood pressure(nDBP) in patients with lacunar infarct were significantly smaller than in patients without lacunar infarct.The ratio of nSBP/dSBP and nDBP/dDBP in SI were smaller than in control group respectively.Conclusions The results indicate that an inappropriately low nocturnal blood pressure,or an excessive fall in nocturnal blood pressure,is associated with lacunar infarct.It is necessary not only to controlhigh blood pressure but also to pay attention to circadian changes of blood pressure during the course of anti-hypertensive treatment.