Constitutional mosaic trisomy 21 and azoospermia: a case report
- VernacularTitle:体质性镶嵌型21三体与无精症一例报告
- Author:
Guohui LU
;
Janice G.EDWARDS
;
Gail WHITMANELIA
;
Tianjian CHEN
;
Ed AMBRUZS
;
Robert G.BEST
- Publication Type:Journal Article
- Keywords:
Constitutional mosaic trisomy 21;
Azoospermia
- From:
Journal of Peking University(Health Sciences)
2005;37(1):94-95
- CountryChina
- Language:Chinese
-
Abstract:
SUMMARY Constitutional full trisomy 21 is a common disorder in which abnormal spermatogenesis has been previously described. However, constitutional mosaic trisomy 21 in an otherwise normal but infertile male has not been explored. We report a case with low level mosaic trisomy 21 in a non-syndrome but azoospermic patient. We also propose that the patient's azoospermia may be related to the constitutional mosaic trisomy 21 and thus resulting in a late onset of testicular failure.
