A Non-rigid Medical Image Registration Algorithm Based on Modally Controlled Free Form Deformation
- VernacularTitle:一种基于模式控制自由变形的非刚性医学图像配准算法
- Author:
Yongming ZHAO
;
Su ZHANG
;
Zhao ZHANG
;
Yazhu CHEN
- Publication Type:Journal Article
- Keywords:
medical images;
non-rigid registration;
free form-deformation;
B-spline;
ridge
- From:Space Medicine & Medical Engineering
2005;18(4):240-245
- CountryChina
- Language:Chinese
-
Abstract:
Objective To register pre-operative MRI/CT images with intra-operative ultrasound images based on vessels visible in both of the modalities. Method A non-rigid registration method of multimodal medical images based on Free Form Deformation(FFD) was proposed. When the images were aligned, the centerline points of the vessels in one image aligned with the intensity ridge points in the other image. Rigid transformation was adopted in global registration while local deformation was described by a Free Form Deformation based on a modally controlled B-spline. The method applied an optimization strategy combining the genetic algorithm with the conjugated gradients algorithm to minimize the objective function. Result Two experiments were designed on phantom and clinical data to evaluate the method. The results demonstrated that the registration method was consistent accurate. The average standard deviation of the final transformation parameters was sub-voxel, sub-millimeter, and within 0.010 radians. Conclusion The results show that the method has good registration accuracy and convergence rate. It can be applied efficiently in the ultrasound-image-guided surgery system.
