The chemical constituents of Ligularia pleurocaulis
- VernacularTitle:侧茎橐吾化学成分的研究
- Author:
Mian ZHANG
;
Chaofeng ZHANG
;
Zhengtao WANG
- Publication Type:Journal Article
- Keywords:
Ligularia pleurocaulis;
6-angeloyloxy-furanoligularenone;
2-oxo-3-hydroxy-eremophila-1(10),3,7(11),8-tetraen-8,12-olide
- From:
Acta Pharmaceutica Sinica
2005;40(6):529-532
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study the chemical constituents of the underground part of Ligularia pleurocaulis (Franch.) Hand-Mazz.. Methods The dried roots and rhizomes of L.pleurocaulis were extracted with methanol. Isolation and purification were performed by silica gel column chromatography and recrystallization etc. Structures of the pure compounds were established on basis of spectral analysis. Results Twelve compounds were obtained from L.pleurocaulis, they were 6-angeloyloxy-furanoligu-larenone (1), 2-oxo-3-hydroxy-eremophila-1(10),3,7(11),8-tetraen-8,12-olide (2), tiglic acid (3), oleanolic acid (4), lupeol (5), β-sitosterol (6), daucosterol (7), caffeic acid (8), emodin (9), 7-methoxy-coumarin (10), ferulic acid (11) and 4-hydroxy-2,5-dimethoxy-benzaldehyde (12). Conclusion Compound 1 is a new eremophilane and compound 2 is a new natural compound. All above compounds were obtained for the first time from L.pleurocaulis.
