Clinical investigation of dermatophagoides farinae drops by sublingual medication in treating children with allergic rhinitis
10.3760/cma.j.issn.1672-7088.2011.05.064
- VernacularTitle:舌下含服粉尘螨滴剂治疗儿童过敏性鼻炎依从性及安全性的临床观察
- Author:
Juan WANG
;
Guilan WANG
;
Miaomiao YAO
- Publication Type:Journal Article
- Keywords:
Sublingual immunotherapy;
Safety;
Compliance
- From:
Chinese Journal of Practical Nursing
2011;27(5):53-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical efficacy,safety and compliance of specific sublingual immunotherapy in allergic rhinitis children. Methods 80 cases of children with allergic rhinitis were randomly divided into the experimental group and the control group with 30 patients in each.The experimental group received dermatophagoides farinae drops by sublingual medication and the control group received standardization allergen vaccine of dermatophagoides pteronyssinus by subcutaneous injection. The observing time lasted 12 months. Clinic symptoms score before and after treatment,safety and compliance between two groups were compared. Results The clinic symptoms score after treatment in both groups were significantly decreased. There was obvious difference between two groups in the incidence of adverse reactions and treatment compliance. Conclusions Sublingual immunotherapy by dermatophagoides farinae drops is effective and comparable to subcutaneous injection therapy by allergen vaccine. It may be a new choice for children with allergy disease.
