A Case of Multiple Bowen's Disease Treated with 5% Imiquimod Cream and Oral Acitretin.
- Author:
Ji Woong KIM
1
;
Jeong Eun KIM
;
Chil Hwan OH
;
Hae Jun SONG
Author Information
1. Department of Dermatology, College of Medicine, Korea University, Seoul, Korea. hjsong@gmail.com
- Publication Type:Case Report
- Keywords:
Acitretin;
Imiquimod;
Multiple Bowen's disease
- MeSH:
Acitretin;
Aminoquinolines;
Biopsy;
Bowen's Disease;
Carcinoma, Squamous Cell;
Cicatrix;
Female;
Follow-Up Studies;
Humans;
Middle Aged
- From:Korean Journal of Dermatology
2008;46(11):1576-1579
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bowen's disease is an in situ squamous cell carcinoma. It usually occurs as a solitary lesion, but it sometimes occurs as multiple lesions. There are many therapeutic options for Bowen's disease. Among the therapies, some methods could be used for multiple lesions. However, the choice of treatment is important because the healing and success rates may vary according to the body site. A 60-year-old female patient presented with multiple erythematous plaques. The diagnosis of multiple Bowen's disease was based on the clinical and histologic features. There were too many suspicious lesions for one local treatment, so we treated the lesions with 5% imiquimod cream and oral acitretin. The imiquimod cream was applied every other day for 33 weeks and oral acitretin was prescribed for 13 weeks. After this treatment, most of the lesions were improved. The follow up biopsy showed only scar tissue. This case demonstrates that a combination of imiquimod cream and oral acitretin might be an alternative treatment option for multiple Bowen's disease lesions.
