Factors related to elderly post-stroke secondary epilepsy
- VernacularTitle:老年脑卒中后继发性癫痫的相关因素分析
- Author:
Tao ZHANG
;
Jiyou TANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2005;9(37):156-157
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Elderly post-stroke secondary epilepsy is the main cause of elderly epilepsy, and has a certain effect on the rehabilitation and prognosis of stroke.OBJECTIVE: To probe into the association of post-stroke epileptic attack with the type, location and size of stroke.DESIGN: A case analysis.SETTING: the Department of Neurology, Qianfoshan Hospital of Shandong Province.PARTICIPANTS: Between January 1999 and December 2004, 68 inpatients (42 males and 26 females) with post-stroke secondary epilepsy, aged 60-83 years with an average of (68±7), were selected from the Department of Neurology, Qianfoshan Hospital of Shandong Province, and all the patients participated in the study voluntarily.METHODS: [1] According to the time of the first attack of post-stroke epilepsy, the patients were divided into early epilepsy (within 2 weeks post stroke) and delayed epilepsy (after 2 weeks post stroke), and the correlation between the time of epilepsy attack and types of stroke was analyzed. [2]Based on the imaging results, the ischemic stroke (including cerebral thrombosis and cerebral embolism) was divided into groups of ＜ 1/4, 1/4-1/2, ＞1/2 of unilateral hemisphere according to the infarcted size, and divided into groups of ＜ 20 mL, 20-40 mL, and ＞ 40 mL according to the amount of cerebral hemorrhage, and the association of epileptic attack with the stroke location and size was analyzed. [3] All the patients received symptomatic treatment, and they were followed up for 6 months to 4 years with an average of 21 months by means of reexamination. [4] The differences of the enumeration data were compared with the χ2 test.RESULTS: All the 68 patients with post-stroke epileptic attack were involved inthe analysis of results. [1] The correlation between the time of epileptic attack and type of stroke: The cases of cerebral hemorrhage and subarachnoid hemorrhage were obviously more in the patients with early epilepsy than in those with delayed epilepsy (10, 2 cases; 4, 0 case, P ＜ 0.05),and the cases of cerebral thrombosis were obviously fewer in the patients with early epilepsy than in those with delayed epilepsy (3, 36 cases, P ＜ 0.05). [2]The association of epileptic attack with the stroke location and size: There were more cases with the infarcted size of 1/4-1/2 and ＞1/2 of unilateral hemisphere than those with the infarcted size of ＜ 1/4 of unilateral hemisphere (26, 17, 9 cases, P＜ 0.05). There were more cases with the 20-40 mL and ＞ 40 mL cerebral hemorrhage than those with ＜ 20 mL cerebral hemorrhage (4, 9, 1 case, P ＜ 0.05). [3] The prognosis of epileptic attack: Of the 21patients with early epilepsy, epilepsy was the first symptom in 6 cases, and no re-attack occurred within 2 weeks in 15 cases. Of the 47 patients with delayed epilepsy, the disease after 1 year was completely controlled in 18 cases,better controlled in 23 cases, and the attack was frequent in 6 cases.CONCLUSION: [1] Early epilepsy is mainly manifested by cerebral hemorrhage, subarachnoid hemorrhage and cerebral embolism, and delayed epilepsy is mainly manifested by cerebral thrombosis. [2] The risk of epilepsy is obviously increased in the patients with the infarcted size over 1/4 of the unilateral hemisphere, and those with ＞ 40 mL cerebral hemorrhage. [3] The prognosis of early epilepsy is better.
