The management of massive bleeding caused by stress ulcer in patients with sever e acute pancreatitis: report of 14 cases
- VernacularTitle:重症急性胰腺炎并发应激性溃疡大出血14例临床分析
- Author:
Shuguo ZHENG
;
Jiahong DONG
;
Shuguang WANG
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;16(1):46-47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate factors influencing the incidence of massive bleeding caused by stress ulcer in severe acute pancreatiti s (SAP) and explore the effectiveness of measures for its prevention and treatme nt. Methods Clinical data of 121 pat ients with SAP were reviewed retrospectively in our center between 1993 and 1998 .The incidence of massive bleeding caused by stress ulcer in SAP, its affecting factors and the results of prevention and treatment were evaluated. Results The incidence of stress ulcer massive b leeding in SAP was 11.6% (14/121). The risk factors included the age of patient s, the severity of the disease, concomitant bile duct lithiasis obstruction, pan creatic abscess, pseudocyst and a history of surgical debridement and drainage. Five out of 6 patients treated conservatively died, while only 1 out of 8 treate d surgically died (P＜0.01). Conclusion Massive bleeding stress ulcer most often occurred in elderly SAP p atients, especially those of biliogenic, with pancreatic abscess and pseudocyst. Somatostain administration effectively decreases the incidence of bleeding. E mergency operation is mandatory when conservative measures fail to stop the bl eeding.
