Intra-arterial chrono-chemotherapy for liver metastasis arised from colorectal cancer
- Author:
Jinhua HUANG
;
Liang ZHANG
;
Peihong WU
;
Weijun FAN
;
Fujun ZHANG
;
Yangkui GU
;
Ming ZHAO
;
Yingsheng CHENG
- Publication Type:Journal Article
- Keywords:
Liver metastasis;
Colorectal cancer;
Chrono-chemotherapy;
Intra-arterial infusion
- From:
Journal of Interventional Radiology
2006;15(8):487-490
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the toxic effects and efficacy of the intra-arterial chrono-chemotherapy on patients with liver metastasis arised from colorectal cancer. Methods Chemotherapy of 42 patients were randomly divided into group A (n = 20) with continuously constant arterial infusion, and group B (n = 22) with arterial chrono-modulated infusion. And the toxic effects and efficacy of two groups were compared. Results A significant difference was found in the toxic effects of digestive system between the two groups. The treatment response was similar in the two groups. Conclusions Intra-arterial chrono-chemotherapy may decrease the toxic effects and improve the life quality of these patients.
