Delayed encephalopathy after acute carbon monoxide poisoning
- VernacularTitle:急性一氧化碳中毒后的迟发性脑病
- Author:
Lei WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2006;10(8):189-192
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To analyze the pathogenesis and clinical manifestations of delayed encephalopathy after acute carbon monoxide poisoning, and to investigate the method of complex treatment and the factors influencing prognosis.DATA SOURCE: Related papers were searched by computer in Chinese Journal Full-text Database (CJFD) from January 1983 to October 2000 and CBMdise with the terms of "acute, carbon monoxide poisoning, delayed,encephalopathy", and the language of paper was limited to Chinese.STUDY SELECTION: The papers relevant to the pathogenesis, clinical manifestation, treatment and prognosis of acute carbon monoxide poisoning were collected preliming screening. Inclusion criteria: ① Randomized controlled trial. ② Blind method was not restricted. Exclusion criteria: The same researches repeated.DATA EXTRACTION: A total of 240 pieces of paper related to acute carbon monoxide poisoning induced eneephalopathy were collected, among which, 24 pieces accorded with inclusion criteria.DATA SYNTHESIS: The pathogenesis of acute carbon monoxide poisoning induced encephalopathy was relatively complex, which should be deeply recognized from the clinical manifestations such as symptom, sign,electroencephalogram, cerebral CT and MRL The therapeutic methods included ①Neural cell agonist, vasodilator, anticoagulant and vitamin ②High pressure oxygen ③ Ultraviolet blood irradation and oxygenation, UBIO. ④ Acupuncture therapy. The factors influencing prognosis of delayed encephalopathy after acute carbon monoxide poisoning were usually related to age, degree of poisoning, complications and cure time.CONCLUSION: Acute carbon monoxide poisoning can cause encephalopathy, which is the result of multiple pathogenesis. There is no special treatment for it until now, and complex treatment should be used, but the curative effect is not ideal, and intellectual disturbance and extremity function disorder of different degree might be left after treatment, and agrypnocoma would exist for a long time.
