A case of pseudo-Cushing's syndrome with unilateral nonfunctioning adrenal adenoma.
- Author:
Won Chul CHANG
1
;
Byung Kook KIM
;
Mi Jin KIM
;
Kwang Ha YOU
;
Hae Jeong JEON
Author Information
1. Department of Internal Medicine, Konkuk University College of Medicine, Seoul, Korea. mijin71@naver.com
- Publication Type:Case Report
- Keywords:
Cushing's syndrome;
Depression;
Adrenal gland;
Adenoma
- MeSH:
Adenoma*;
Adrenal Glands;
Adrenocorticotropic Hormone;
Aged;
Alcoholism;
Cushing Syndrome;
Depression;
Depressive Disorder;
Dexamethasone;
Female;
Humans;
Korea;
Obesity
- From:Korean Journal of Medicine
2005;69(2):216-221
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A pseudo-Cushing's state can be defined as some or all of the clinical features of Cushing's syndrome together with some evidence for hypercortisolism. It may be related to depression, alcohol abuse and obesity. Its manifestation may be transient and resolved with abstinence from causing factors. We report a case of a 70-year-old woman with unilateral nonfunctioning adrenal adenoma and geriatric depressive disorder, which diagnosed by Geriatric Depression Scale (GDS). She showed clinical and/or biochemical features of Cushing's syndrome. Low dose and high dose dexamethasone suppression tests were not identical to those in ACTH independent Cushing's syndrome. Few cases of pseudo-Cushing's syndrome were reported previously in Korea but there was no report about pseudo-Cushing's syndrome combined with nonfunctional adrenal adenoma.