Effect of functional magnetic stimulation on the treatment of neurogenic bladder
- VernacularTitle:功能性磁刺激治疗神经原性膀胱的疗效追踪
- Author:
Ning ZHOU
;
Min LU
;
Xiaolin HUANG
;
Xinhua DING
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2006;10(44):190-192
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Functional magnetic stimulation (FMS) is characterizedby safe, unwounded and non-side effect. At present, it has been used incentral nervous conduction, recovery from nervous exhaustion, bone healing, treatment of neural disorder, research of brain function, and so on;meanwhile, it also can improve urination dysfunction.OBJECTIVE: To pursue investigating the effect of FMS on the treatment of neurogenic bladder.DESIGN: Self controlled study pre- and post-treatment.SETTING: Department of Rehabilitation Medicine, Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technique.PARTICIPANTS: Twenty patients with neurogenic bladder were recruited in the Department of Rehabilitation Medicine, Tong ji Hospital, Tongji Medical College, Huazhong University of Science and Technique from June 2003 to June 2004. Of them, 12 patients with neurogenic bladder were caused by spinal cord injury and 8 by other reasons under urinary dynamic examinations.METHODS: Twenty patients with neurogenic bladder underwent S3 never root and bladder FMS by MagLite magnetic stimulation system (Dantec Company, Denmark), for 20 successive times, twice a day, five days a week and 4-6 weeks as a course. The interval was 2 seconds and the frequency was 5 minutes for once. Parameters were designed as the following: intensity: 70％-80％maximal magnetic intensity; frequency: 5 Hz; impulse length: 1 ms.MAIN OUTCOME MEASURES: Parameters were observed pretreatment, post-treatment immediately and at 1 and 3 months: ① Urine frequency: the mean voided volume and the maximal voided volume; ②Scores of quality of life (QOL): Scores ranged from 0 to 6 points. The higher the scores were, the poorer the QOL was. ③ International lower urinary tract symptoms (LUTS) scores: There were 7 questions with the scores of 0-35. The higher the scores were, the severer the symptoms were.RESULTS: All 20 patients were involved in the final analysis. ① Effect of urination on QOL scores: Scores were decreased post-treatment as compared with those pretreatment (3.17±1.53, 4.58±1.00, P ＜ 0.01), and scores were increased within 1 and 3 months post treatment but were still lower than those pretreatment (P ＜ 0.01). ② LUTS scores: Scores were decreased post-treatment as compared with those pretreatment (21.42±5.00,28.08±1.51, ,P ＜ 0.01), and scores were increased within 1 and 3 months post-treatment but were still lower than those pretreatment (P ＜ 0.01). ③Times of urination were decreased, but the mean voided volume and themaximal voided volume were increased (P ＜ 0.05); in 1 month post-treatment, each parameter was decreased but was still superior to that pretreatment (P ＜ 0.05); at 3 months post-treatment, each parameter was still decreased, but there was no significant difference of mean voided volume from that pretreatment (P ＞ 0.05), and other parameters were superior to those pretreatment (P ＜ 0.05); there was no significant difference at eachtime point post-treatment (P ＞ 0.05).CONCLUSION: FMS can partly improve the symptoms of voiding dys-function and improve the quality of life.
