Clinical observation of multiple bone metastases with153Sm-EDTMP
- VernacularTitle:153钐-乙二胺四甲基膦酸治疗多发性骨转移癌骨痛疗效观察
- Author:
Jingbin SHI
;
Hui FAN
;
Yongmei HAO
- Publication Type:Journal Article
- From:Clinical Medicine of China
2001;17(5):370-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility of 153 Sm-EDTMP for multiple bone metastasis.Methods 32 patients with multiple bone metastases were treated with 153 Sm-EDTMP injected into the veins,0.4～1.0 mci/kg,of which 7 cases received therapy for 2～3 times.Results 53.1%(17/32)was relieved completely,25.0%(8/32)was relieved partially and 9.4%(3/32)was relieved slightly.No effects were found in 12.5%(4/32).The overall effective rate was 78.1%.Side effects that were the decreasing of WBC and PLT were found in 15.6%(5/32),which rose to the preoperative levels within 6～8 weeks.Conclusion Internal radiotherapy with 153 Sm-EDTMP is safe and effective in the treatment of multiple bone metastases.
