β-AR density relativity of porcine myocardial tissue and circulating lymphocytes and its significance
- VernacularTitle:猪外周血淋巴细胞与心肌细胞β受体密度的相关性及其意义
- Author:
Zitong HUANG
;
Tong WANG
;
Jiamin QIU
- Publication Type:Journal Article
- From:
Chinese Journal of Emergency Medicine
2001;10(2):87-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study β-AR density relativity between porcine myocardial tissue and circulating lymphocytes and clinical significance .Methods 48 porcines(seven months old),were taken a few of myocardial tissue and peripheral blood.Assay β-AR density with radioactive isotope to study the relativity.Results Scatter plot of β-AR density circulating lymphocytes and myocardial tissue showed linear Correlation(r=0.845,P<0.001 Y=0.002527X+0.726).Conclusion There was obvious correlation on β-AR density in circulating lymphocytes and myocardial membrane of pigs.Determination of β-AR density in circulating lymphocytes can reflect alteration of that in myocardial tissue.Therefore,we can use it to monitor and investigate self-induced and drug-induced β-AR changes.