Clinical observation of levonorgestrel-releasing intrauterine system in treatment of endometriosis
10.3760/cma.j.issn.1673-4904.2011.12.007
- VernacularTitle:左炔诺孕酮宫内缓释系统治疗子宫内膜异位症的临床观察
- Author:
Meixia KANG
;
Jinjie LI
;
Liya YOU
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Dysmenorrhea;
Levonorgestrel-releasing intrauterine system
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(12):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of levonorgestrel-releasing intrauterine system(LNGIUS) in the treatment of endometriosis. Methods Fifty-three patients suffering from endometriosis were placed LNG-IUS in uterine cavity after menstruation. The efficacy 3,6,12 months after LNG-IUS placement was observed and compared. Results The scores of dysmenorrhea, deep dyspareunia, menstrual anus pain 3,6,12 months after LNG-IUS placement were lower than those before LNG-IUS placement (P < 0.05 ).CA125 [(21.8±12.5) kU/L]and destradiol [(78.8±45.5)ng/L] 12 months after LNG-IUS placement were improved than those before LNG-IUS placement and 3,6 months after LNG-IUS placement [CA 125:(36.3±17.5), (33.5±15.6), (28.2 ± 11.7) kU/L,destradiol: (40.4 ± 28.6), (42.5 ± 31.5), (56.5 ± 36.2) ng/L](P < 0.05 ). The menstrual blood volume was less 6,12 months after LNG-IUS placement than that before LNG-IUS placement (P<0.05), and the quality of life was improved( P < 0.05 ). Conclusion LNG-IUS can be safe and effective treatment of patients with endometriosis, and less side effects.