Challenges in research and development of Traditional Chinese Medicines
- VernacularTitle:中药研究开发的挑战
- Author:
Changxiao LIU
;
Duanyun SI
;
Haitang XIE
- Publication Type:Journal Article
- Keywords:
Traditional Chinese Medicine;
challenge;
research;
development;
efficacy;
safety;
new technique
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2007;12(10):1122-1129
- CountryChina
- Language:Chinese
-
Abstract:
In this review, the author analyzed the challenges in modern research and development of Traditional Chinese Medicine (TCM) products. Chinese traditional and herb drugs have gained interest from the international medical, biomedical and pharmaceutical institutions as potential source of valuable medicinal agents. For the researches and development of TCMs, the first challenge is to evaluate the efficacy, pharmacological properties, action mechanism and active chemical constituents. The second one is to summarize the issues for developing safety research methodologies, to improve the quality and enhance the value of research in TCM and to provide appropriate evaluation methods to facilitate the regulation and registration of TCM products, and the third is to study drug metabolism and pharmacokinetics, and the fourth is to apply new "-omics" techniques and tools in new revolution in drug discovery-development and to impact on modern research of TCM products. This interest is needed to apply modern research on the development and exploration of the promising medical potential resources of Chinese traditional and herbal drugs, especially from medicinal plants.
