Current Status of Targets and Assays for Anti-HIV Drug Screening
- Author:
Renrong TIAN
;
Qingjiao LIAO
;
Xulin CHEN
- Publication Type:Journal Article
- Keywords:
Anti-HIV;
Targets;
Assays;
Drug screening
- From:
Virologica Sinica
2007;22(6):476-485
- CountryChina
- Language:Chinese
-
Abstract:
HIV/AIDS is one of the most serious public health challenges globally. Despite the great efforts that are being devoted to prevent, treat and to better understand the disease, it is one of the main causes of morbidity and mortality worldwide. Currently, there are 30 drugs or combinations of drugs approved by FDA. Because of the side-effects, price and drug resistance, it is essential to discover new targets, to develop new technology and to find new anti-HIV drugs. This review summarizes the major targets and assays currently used in anti-HIV drug screening.