Cyclosporin A in High Risk Penetrating Keratoplasty.
- Author:
Changkook KIM
1
;
Hungwon TCHAH
Author Information
1. Department of Ophthalmology, Asan Medical Center, College of Medicine Ulsan University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cyclosporin A;
Penetrating keratoplasty;
High risk group
- MeSH:
Cornea;
Cyclosporine*;
Graft Survival;
Humans;
Keratoplasty, Penetrating*;
Survival Rate;
Transplants
- From:Journal of the Korean Ophthalmological Society
2001;42(8):1139-1142
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To conform the effectiveness of Cyclosporin(CsA) in penetrating keratoplasty(PKP), we compared the survival rate of grafts between CsA-used group and CsA-unused group(control group) in high risk patients. MATERIAL AND METHOD: High risk cornea was defined as vascularization in 3 or 4 quadrants, recurrent graft or corneal surface disease. We reviewed the 74 eyes(74 patients) which received penetrating keratoplasty with high risk cornea, and compared the survival rate between CsA-used group and control group. RESULT: Twenty-nine of the 74 patients were treated with CsA(17 patients with topical CsA and 12 with oral CsA ). The survival rate of CsA-used group was not superior to that of control group. CONCLUSION: CsA seems not to be effective in graft survival of high risk PKP.
