Anaphylactic Shock by Intravenous Injection of Cimetidine: A case report.
- Author:
Ji Ho RYU
1
;
Yong Su LIM
;
Hyuk Jun YANG
;
Jae Kwang KIM
;
Jung Ho SHIN
;
Gun LEE
;
Wook JIN
;
Sung Youl HYUN
Author Information
1. Department of Emergency Medicine, Thoracic Surgery, Ghil Medical Center, Gachon Medical School, Incheon, Korea. yongem@netian.com
- Publication Type:Case Report
- Keywords:
Anaphylactic shock;
Cimetidine
- MeSH:
Anaphylaxis*;
Bradycardia;
Central Nervous System;
Cimetidine*;
Gynecomastia;
Heart Arrest;
Hypersensitivity;
Hypotension;
Incidence;
Injections, Intravenous*;
Male;
Nephritis, Interstitial;
Urticaria
- From:Journal of the Korean Society of Emergency Medicine
2002;13(3):377-379
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cimetidine is a well-tolerated H2-receptor antagonist widely used in the treatment of gastroduodenal diseases and allergic reactions such as urticaria. Numerous adverse reactions have been attributed to cimetidine, which is understandable in view of the attention and scrutiny the drug has received, its widespread use, and its systemic effects. The incidence of general side effects is less than 2%. The drug has caused an array of central nervous system disturbances, gynecomastia, and rarely hepatotoxicity, interstitial nephritis, bradycardia, hypotension, and even cardiac arrest. Cardiovascular side effects are extremely rare and have occurred during rapid intravenous injection. We report a case of anaphylactic shock after rapid intravenous injection of cimetidine.
