Diagnostic value of serum myoglobin and cardiac troponin in patients with acute myocardial infarction and corresponding reference assessment
- VernacularTitle:Mb和cTn对AMI诊断的价值及文献评价
- Author:
Juquan ZHAO
;
Jiaoyuan LU
- Publication Type:Journal Article
- Keywords:
Myoglobin;
Cardiac Troponin;
Myocardial Infarction;
Evidence Based Medicine;
Documentation;
Evaluation Studies
- From:
International Journal of Laboratory Medicine
2008;29(5):388-391
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of serum myoglobin (Mb) and cardiac troponin (cTn) in patients with acute myocardial infarction (AMI) by reviewing and evaluating the corresponding references with evidence-based medicine (EBM) theory.Methods All references (including papers,reviews and abstracts) of CNKI-CHKD,CMCC(1994-2005)and EMCC(1995-2005) were collected and retrospectively analyzed according to evidence based medicine (EBM) standard,with Mb cTn as the detected indices for diagnosing AMI.Results In the searched period of 1994-2005,123 papers were published (93 pieces were written in Chinese,and 30 were written in English). In most references,the authors set clinical control trial (CCT) (Chinese: 92.5%;English: 53.3%),blind control trial (Chinese: 19.4%;English: 10.0%) and/or random control trial (RCT) (Chinese: 9.7%;English: 16.7%). The respective reference ranges weren′t provided in 42 pieces of articles.Conclusion The analytic result of the references in home and aborad indicates combined detection of Mb and cTnI posseses favourite sensitivity and specificity,which contributes to the early diagnosis of acute myocardial infarction.
