Determination of serum prealbumin and C-reactive protein in 68 burn patients and its clinical significance
- VernacularTitle:68例烧伤患者血清PA和CRP的检测及其临床意义
- Author:
Hui CHEN
;
Yingchun ZHOU
;
Ping GUAN
- Publication Type:Journal Article
- Keywords:
Burn;
Prealbumin;
C-reactive protein
- From:
International Journal of Laboratory Medicine
2008;29(5):416-417
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of serum prealbumin (PA) and C-reactive protein (CRP) in burn patients and its clinical significance.Methods Sixty eight cases of burn patients were divided into two groups,group Ⅰ [n=38,with total burn surface area less than 15% of total body surface area (TBSA)] and groupⅡ(n=30,with total burn surface area more than 50% of TBSA). Thirty healthy people were set as healthy control group. Particle enhanced immunoturbidimetic assay was applied to detecting the serum levels of PA and CRP for all subjects on the day 1 after burns.Results The CRP level was much higher and serum level of PA was much lower in group Ⅱ than that of group Ⅰ,respectively. There existed significant negative correlation between PA and CRP level.Conclusion The level of serum PA decreases significantly along with total burn surface area expansion. PA can be used as a sensitive marker for estimation of inflammation degree after burns.