Surveillance of Antibiotic Susceptibility of Neisseria gonorrhoeae Isolated from Ten Cities of China from 1993～ 1998

VernacularTitle:1993～ 1998年中国十城市分离的淋球菌对抗生素的敏感性监测
Author: Shunzhang YE
Publication Type:Journal Article
From: Chinese Journal of Dermatology 2001;34(3):175-177
CountryChina
Language:Chinese
Abstract: Objective To investigate the antimicrobial susceptibility of Neisseria gonorrhoeae isolated from 10 cities of China, and to provide reference for the formulation of treatment guideline and making control strategy. Methods Agar dilution was used to detect antimicrobial susceptibility and acidometric method for PPNG testing. Results A total of 3186 gonococcal isolates were tested from 1993 to 1998. The resistant rate for penicillin was 66.70％ . PPNG isolates accounted for 8.14％ . Tetracycline－ resistant isolates accounted for 93.02％ , and high level tetracycline－ resistant isolates (TRNG) accounted for 4.65％ . The resistant rate for ciprofloxacin was also high (34.25％ ). The resistant rates for spectinomycin and ceftriaxone were 0.44％ and 0.57％ respectively. Conclusions The gonococcal isolates are highly resistant to penicillin, tetracycline, and ciprofloxacin, while still sensitive to spectinomycin and ceftriaxone. These results suggest that the present treatment for gonorrhea can still be used.