One New Method of Nucleic Acid Amplification-Loop-mediated Isothermal Amplification of DNA
- Author:
Xueen FANG
;
Jian LI
;
Qin CHEN
- Publication Type:Journal Article
- Keywords:
Nucleic acid amplification;
Loop-mediated isothermal amplification (LAMP);
Application
- From:
Virologica Sinica
2008;23(3):167-172
- CountryChina
- Language:Chinese
-
Abstract:
Loop-mediated isothermal amplification (LAMP) is a novel nucleic acid amplification method, which amplifies DNA with high specificity, sensitivity, rapidity and efficiency under isothermal conditions using a set of four specially designed primers and a Bst DNA polymerase with strand displacement activity. The basic principle, characteristics, development of LAMP and its applications are summarized in this article.
