Clinical significance of serum cystatin C and urinary TGFβ1 in severe eclampsism
- VernacularTitle:血清胱抑素C与尿转化生长因子β1在重度子痫前期患者中的临床意义
- Author:
Xudong GU
;
Jianbo CHEN
- Publication Type:Journal Article
- Keywords:
Eclampsia;
Chalones;
Intercellular Signaling Peptides and Proteins
- From:
International Journal of Laboratory Medicine
2008;29(8):693-694
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of surem eystatin C and urinary transforming growth factorβ1(TGF-β1)in patients with severe eclampsism.Methods Serum cystatin C and urinary transforming growth factorβ1 were examined in 35 severe eclampsism women(experiment group,n=35)and normal late pregnant women(control group,n=35).Results The levels of serum cystatin C and urinary transforming growth factorβ1 were both significantly increased in experiment group than those in control group(both P<0.01).The serum level of cystatin C was positively correlative with urinary TGF-β1 level in experiment group(r=0.581,P<0.05).Conclusion The detection of serum cystatin C and urinary transforming growth factorβ1 is useful to assess renal function lesion in patients with severe eclampsism,which contributes to the diagnosis and treatment of severe eclampsism.
