Research on nosocomial infection and drug resistance of Pseudomonas aeruginosa
- VernacularTitle:铜绿假单胞菌医院感染及耐药性的研究
- Author:
Ming LEI
;
Zhibin ZHU
- Publication Type:Journal Article
- Keywords:
Pseudomonas Aeruginosa;
Cross infection;
Drug resistance,Bacterial;
Anti Bacterial Agents
- From:
International Journal of Laboratory Medicine
2008;29(7):592-594
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and drug resistance state of Pseudomonas aeruginosa, so as to offer reasonable experimental data for clinical therapy. Methods A statistic analy- sis for the specimen souree, distribution of infected departments and drug resistance state to 441 iso- lates was conducted in a retrospective way. Results Among 441 strains, 357 (80. 95%) were isolated from sputum species. The department with the highest isolating rate was ICU (26.5%), followed by department of respiratory disease (20. 63 %), department of neurosurgery (19.05 %) and department of geriatrics (17. 01%). The most sensitive antibiotic was Meropenem, which total drug resistance rate was 13. 61%; the most insensitive antibiotic was ampicillin-sulbactam, which total drug resistance rate was 91.38%. The drug resistance rate of P. Aeruginosa was increasing year by year. Conclusion Clinical isolates of P. Aeruginosa mostly come from sputum samples and ICU, and they are highly and multidrug resistant to various antibiotics.
