The relationship of plasma level of brain natriuretic peptide and left ventricular hypertrophy in patients with essential hypertension
- VernacularTitle:血浆脑利钠肽水平与原发性高血压左室肥厚的关系
- Author:
Qing WANG
;
Lili DUAN
;
Bin DU
- Publication Type:Journal Article
- Keywords:
Brain Natriuretic Peptide;
Hypertension;
Hypertrophy,Left Ventricular
- From:
International Journal of Laboratory Medicine
2008;29(7):602-603
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of plasma level of brain natriuretic peptide (BNP) and left ventricular hypertrophy (LVH) in patients with essential hypertension. Methods The plasma level of BNP was measured with electrochemiluminescence immunoassay method in 32 hyper- tensive patients without left ventricular hypertrophy (LVH) (NLVH group), 30 patients with essen- tial hypertension with LVH (LVH group), and 30 healthy adults (control group). Doppler echocar- diography was employed to determine left ventrieular mass index (LVMI) and observe the correlation of plasma BNP level with LVMI. Results The plasma BNP level was significantly elevated in LVH group than that of NLVH group and control group (P<0.01). The plasma BNP level was significant- ly higher in NLVH group than that of control group (P<0.01). BNP level was positively correlated with LVMI in hypertensive patients with LVH (r= 0.64, P<0. 01). Conclusion BNP level may reflex the degree of left ventricular hypertrophy in patients with essential hypertension.
