Sex differences in therapeutic outcomes in patients undergoing coronary stenting
- VernacularTitle:冠状动脉支架置入患者治疗结局的性别差异
- Author:
Handong ZHU
;
Guoying ZHU
;
Xi SU
;
Dan SONA
;
Jian PENA
;
Guohong CHEN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2008;12(35):6981-6984
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Previous studies have shown that there are some significantly gender-related differences in coronary heart disease between women and men.It is not clear whether the outcomes have affected by gender.OBJECTIVE:To analyze the outcomes of follow-up after coronary stenting,and to investigate the sex diffefence.DESIGN,TIME AND SETTING:The prospective follow-up was performed at the Wuhan Asia Heart Hospital from January 2004 to December 2005.PARTICIPANTS:267 patients who suffered from coronary artery disease and treated with percutaneous coronary intervention were involved in the present study and followed up for 3 years,including 52 females and 215 males,averagely(59.4±7.5)years old.Imfarction in 3 levels were considered to be scccessful.Follow-up in out-patient clinic was conducted regularly.Six monks after implantation,telephone follow-up was done;questionnaire follow-up was performed every year.Average follow-up time was(20±7)months.MAIN OUTCOME MEASURES:Baseline clinical and angiographic characteristics,follow-up outcomes after 3 years of implantation after coronary stenting were compared between 52 females and 215 males.lower significantly than those in men.During the 3-year follow-up,no significant differences were observed between women and men regarding death,major adverse cardiovascular events,and recurrent typical ischemia.The proportion of symptom remission,life quality improvement was similar between women and men.In multivariable analysis,sex was not anindependent predicator for long-term outcomes of coronary stenting(OR 0.819,95% CI 0.41 to 1.79).CONCLUSION:Women with coronary artery disease are older than men and have more comorbidities.Long-term outcomes have improved in women after coronary stenting.Therapeutic outcome is not correlated to sex.
