Current application of hydroxyapatite nanoparticles in tumor field
- VernacularTitle:纳米羟基磷灰石在肿瘤领域的应用现状
- Author:
Yan LI
;
Huashan SHI
;
Ge LI
- Publication Type:Journal Article
- Keywords:
Hydroxyapatite and tumor in both Chinese and English
- From:
Chinese Journal of Tissue Engineering Research
2008;12(32):6393-6396
- CountryChina
- Language:Chinese
-
Abstract:
Hydroxyapatite has already been considered as an excellent medical biomaterial.and nanometer hydroxyapatite possesses special characteristics.Hydroxyapatite nanoparticles can inhibit the growth of a wide range of cancer cells.but have no effect on normal cells.thus it has a better selectivity in the treatment of cancer.The anti-tumor mechanism of nano-hydroxyapatite is relevant on the following factors:role in the cell membrane,affecting DNA synthesis,inducing cell cycle blockage and apoptosis,impacting the activity of telomerase.This study is designed to introduce the specific structure and characterjstics of nano-hydroxyapatite,analyze the research progress of nano-hydroxyapatite in tumor field.and discuss the possibility of nano-hydroxyapatite as a new anti-cancer drug in clinical application.
