Influence of Lipofundin vs Intralipid on lipid and energy metabolism of surgical cirrhotic patients
- VernacularTitle:不同碳链脂肪乳剂对肝脏外科患者脂肪及肝脏能量代谢的影响
- Author:
Huanlong QIN
;
Zhaohan WU
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;16(4):240-242
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence of Lipofundin vs Intralipid on lipid energy metabolism of cirrhotic patients undergoing surgery.Methods Twenty-five patients with liver disease were randomly assigned to two PN groups:LCT group(n=12) and MC/LCT group (n=13).Fat energy in group LCT was supplied by 20%-Intralipid,Group MCT/LCT was supplied by 20%-Lipofundin.All patients were on parenteral nutrition for 7 days.Intravenous fat tolerance test (IVFTT) was measured at pre-op,post-op d1、post-op d7.Carnitine （CNT） level in serum and urine,and AKBR were tested at the pre-op、post-op d1、d7.Results The elimination rate of the MCT was faster than that of LCT at pre-op and post-op d7,the elimination rate of LCT at post-op d1 was faster than that of at pre-op and post-op d7.Serum CNT increased in both groups,urine CNT markedly decreasd at postoperation,but in LCT group CNT was at lower level as compared with MCT group at post-op d7,P＜0.05.AKBR was markedly decreased in both groups post-op,but at post-op d7,AKBR in MCT group was higher than in LCT group,P＜0.01.Conclusions These results indicated that Lipofundin was an ideal energy source for the cirrhotic patients.
