Molecular Modification of a HSV-1 Protein and Its Associated Gene Transcriptional Regulation
10.1007/s12250-008-2994-z
- Author:
Yanchun CHE
;
Li JIANG
;
Qihan LI
- Publication Type:Journal Article
- Keywords:
Modification;
Herpes simplex virus type (HSV-1);
Transcriptional regulation
- From:
Virologica Sinica
2008;23(6):394-398
- CountryChina
- Language:Chinese
-
Abstract:
The molecular modifications of Herpes Simplex Virus Type Ⅰ (HSV-1) proteins represented by acetylation and phosphorylation are essential to its biological functions.The cellular chromatin-remodeling/assembly is involved in HSV-1 associated gene transcriptional regulation in human cells harboring HSV-1 lytic or latent infections.Further investigation on these biological events would provide a better understanding of the mechanisms of HSV- 1 viral gene transcriptional regulation.
