Pathogenetic Consequences of Cytomegalovirus-Host Co-evolution
10.1007/s12250-008-3003-2
- Author:
Gerardo ABENES
;
Fenyong LIU
- Publication Type:Journal Article
- Keywords:
Cytomegalovirus;
Co-evolution;
Pathogenesis
- From:
Virologica Sinica
2008;23(6):438-448
- CountryChina
- Language:Chinese
-
Abstract:
Co-evolution has been shown to result in an adaptive reciprocal modification in the respective behaviors of interacting populations over time.In the case of host-parasite co-evolution,the adaptive behavior is most evident from the reciprocal change in fitness of host and parasite-manifested in terms of pathogen survival versus host resistance.Cytomegaloviruses and their hosts represent a pairing of populations that has co-evolved over hundreds of years.This review explores the pathogenetic consequences emerging from the behavioral changes caused by co-evolutionary forces on the virus and its host.
