The clinical significance of detecting the activites of T cells and NK cells in the peripheral blood of patients with colorectal cancer
- VernacularTitle:大肠癌患者外周血T细胞亚群和NK细胞活性检测的临床意义
- Author:
Biao XIONG
;
Youbao ZOU
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Subset,T-Lymphocyte;
Killer Cells,Natural
- From:
International Journal of Laboratory Medicine
2008;29(10):892-893
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between immune condition and stages of tumor in patients with coloreetal cancer by detecting the activites of peripheral blood T cells and NK cells. Methods The activites of T cells and NK cells in peripheral blood from 90 patients with cancer of colon and 40 healthy controls were detected by flow cytometry. Results The CD3+ ratio,CD4+ rati-o,CD4+/CD8+ and NK cells were decreased in cancer of colon group. CD8+ ratio was increased com-pared with that of healthy control group. This chang became more significant following by accreseence of Dukes classification. Conclusion The cellular immune function disorder exists in cancer of colon pa-tients which a aggravation with the pathogenetic condition progress.
