Relation between vascular endothelial cell proliferation and serum lipoprotein (a)level following coronary arterial stent implantation An analysis of 128 cases
- VernacularTitle:冠状动脉支架置入后血管内皮细胞增生与血脂蛋白(a)变化128例分析
- Author:
Junxia LI
;
Yuying ZHAO
;
Li ZHANG
;
Yali WEI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2008;12(52):10378-10380
- CountryChina
- Language:Chinese
-
Abstract:
A total of 128 patients with coronary heart disease/angina pectoris who underwent coronary arterial stent implantation were collected in this study between January and December 2002.① At 6-18 months of follow up,coronary artery angiography (CAG) showed that diameter stenosis rate ＞I 50% was considered the restenosis.While,36 out of 128 lesions had restenosis,and the rate was 28.1%.Serum lipoprotein (a) level in the restenosis group was significantly higher than non-restenosis group (P ＜ 0.01).②All patients were divided into high lipoprotein (a) group (the concentration ≥ 230 mg/L) and low lipoprotein (a) group (the concentration ＜ 230 rag/L).Restenosis rate in the high lipoprotein (a) group was significantly higher than low lipoprotein (a) group (P ＜ 0.05).Intravascular ultrasound showed that area and volume of newborn endomembrane in the high lipoprotein (a) group were significantly higher than slow lipoprotein (a) group after coronary arterial stent implantation (P ＜ 0.01).③ Correlation analysis suggested that.lipoprotein (a) was positively correlated with area and volume of newborn plaque (P ＜ 0.05).
