Allogenic single-lung transplantation for chronic obstructive pulmonary disease in 4 cases
- VernacularTitle:慢性阻塞性肺疾病4例单肺移植
- Author:
Dong CUI
;
Linhu GE
;
Jianxing HE
;
Xin XU
;
Hanzhang CHEN
;
Weiqiang YIN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2008;12(53):10571-10574
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data of 4 patients with chronic obstructive pulmonary disease who underwent allogenic single-lung transplantation were retrospectively analyzed. All cases received corpse donor lungs. One case with diffuse emphysema underwent right lung transplantation. and 3 received left lung transplantation. including one underwent fight lung volume reduction during surgery and 2 cases underwent right lung volume reduction post-transplantation. The inductive treatment with daclizumab or antithymocyte globulin was done and the rejection was prevented with Tacrolimus. mycophenolate and prednisone. The surgery was successfulin 4 cases. One case developed acute rejection on the fifth day post-transplantation. and controlled using methylprednisolone. Two cases discharged successfully, of whom one lived more than 2 years. Two cases died 74 days and 77 days after lung transplantation. respectively.
