Processing of the cerebellum in speech production by functional magnetic resonance imaging
- VernacularTitle:功能磁共振验证言语产生中的小脑加工
- Author:
Shengyong XIAO
;
Hongchang ZHAI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2008;12(48):9585-9588
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: The right hemisphere of the cerebellum was involved in linguistic function was disputed. In addition,there was no research report which suggested that the left hemisphere of the cerebellum participated in language processing as same as the right hemisphere. OBJECTIVE: To explore the activation of fight cerebellar hemisphere involved in speech production as well as to discuss the role of left cerebellar hemisphere in speech by means of examining the activated brain regions related the processing of speech production. DESIGN,TIME AND SETTING: Comparison observation,performed at Department of Magnetic Resonance,the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine between June and July 2008.PARTICIPANTS: Eight normal undergraduate with right-handed but without achromatopsia or hypochromatopsia volunteered to participate in the study. METHODS: Block design was used in this study. Subjects were required to generate a verb related to the Chinese 2-word noun represented visually and the functional scans were performed at the same time,and then the functional data were dealt with analysis of functional neuroimages (AFNI) and analyzed by drawing region of interest (ROI).MAIN OUTCOME MEASURES: The activation location,coordinate,voxel and the brain activation picture. RESULTS: Verb generation not only activated the right cerebellar hemisphere,but also the left cerebellar hemisphere.And the volumes activated in the left were larger than in the right. CONCLUSION: The lingual function of cerebellum is not only limited in the right,the left cerebellar,hemisphere may be engaged the processing of lingual function.