Simultaneous pancreas-kidney transplantation for type 2 diabetes mellitus complicated with endstaged renal disease in 1 case
- VernacularTitle:胰肾联合移植治疗2型糖尿病合并终末期肾病1例
- Author:
Bole TIAN
;
Xubao LIU
;
Weiming HU
;
Fanghai HAN
;
Gang MAI
;
Jichun ZHAO
;
Li WANG
;
Huimin LU
;
Yi ZHANG
;
Zhaoda ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(5):979-982
- CountryChina
- Language:Chinese
-
Abstract:
We performed a simultaneous pancreas-kidney transplantation (SPK) for type 2 diabetes complicated with end-staged renal disease (ESRD) in March, 2007. The recipient was a 65-year old male, who suffered type 2 diabetes for 15 years and renal dysfunction for 5 years and other diabetic complications such as retinopathy and peripheral neuropathy. SPK was performed successfully for him, in which the kidney was placed in the left iliac fossa, while the pancreas in the right iliac fossa, with an entedc drainage for pancreas exocrine and a systemic drainage for endocrine. Serum C-peptide, creatinine and blood urea nitrogen reached normal levels on day 1,4 and 11 post-transplant, respectively. Blood glucose became stabilized gradually to normal level and therefore the injected insulin was stopped on day 16 post-transplant. Oral glucose tolerance test (OGTT) showed the function of grafted pancreas was normal after 3 weeks of transplant, and no transplant-related complications occurred. With the recipient followed up for 20 months, both his blood glucose level and renal function maintained normal without using insulin.
