Clinical distribution and drug resistance of 747 strains of nonfermenters
10.3760/cma.j.issn.1673-4130.2009.03.007
- VernacularTitle:747株非发酵菌临床分布及耐药性分析
- Author:
Li ZHANG
;
Xiaobing ZHANG
;
Lihua ZHANG
- Publication Type:Journal Article
- Keywords:
Gram-negative bacteria;
Drug resistance,bacterial;
Cross infection
- From:
International Journal of Laboratory Medicine
2009;30(3):226-228
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the drug resistance and the clinical distribution of nonfer-menters in the recent three years in our hospital, and to provide basis for rational use of antibacterials.Methods The bacteria were identified by VITEK32 bacteria identification system and Kirby-Bauer(K-B) method was used for the antibiotics susceptibility test. The data was statistically analyzed. Results A total of 747 strains of nonfermenters were isolated from various clinical specimens during Jan 2005 to Dec 2007. The most common nonfermenters were Pseudomonas aeruginosa, followed by Acineto-bacter baumannii, Stenotrophomonas maltophilia and Acinetobacter lowfii. The isolation rate of non-fermenters was the highest from sputum specimens(59.3 %). These bacteria had various resistances to all detected antibiotics. These nonfermenters were lowly resistant to imipenem and piperaeillin/tazo-bacam. The resistance rate of Stenotrophomonas maltophilia to minocycline, imipenem and levofloxa-cin was 1.2%, 3. 45 and 10. 3% respectively. Conclusion The nonfermenters are main pathogenic bacteria of nosoeomial infection, they are isolated from different clinical specimens and their drug-re-sistance is variant and multiple. To reduce-the production of drug-resistance and control the nosocomi-cal infection, the specimens must be collected and detected timely; the antibiotics should be selected according to the results of susceptibility test.
