Effect of ketamine preemptive analgesia on postoperative pain and recovery in laparoscopic cholecystectomy
- VernacularTitle:静脉低剂量氯胺酮超前镇痛对腹腔镜胆囊切除术后苏醒和疼痛的影响
- Author:
Zhiqing ZOU
;
Li LI
;
Zhouquan WU
- Publication Type:Journal Article
- Keywords:
Ketamine;
Laparoscopic cholecystectomy;
Analgesia
- From:
The Journal of Clinical Anesthesiology
2009;25(5):387-388
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of ketamine preemptive analgesia on postoperative pain and recovery in laparoscopic cholecystectomy(LC). Methods Eighty LC patients under general anesthesia with propofol and remifentany were randomly divided into two groups of PR and PRK with 40 cases each. The patients in group PRK were given additional low-dose ketamine 0.3 mg/kg before skin incision. Recovery from anesthesia was evaluated at 30 min, 1 h and 12 h after surgery by SS and VRS scoring. Results There were no significant differences in the time for regaining spontaneous breathing,opening eyes and extubation between the two groups. But recovery of anesthesia was with less restlessness and VRS pain scores, better sedation in group PRK than those in group PR (P< 0.05). Conclusion Preemptive intravenous analgesia with low-dose ketamine has the advantage of quicker recovery from anesthesia with less incidence of restlessness and pain in LC patients.
