Analysis of drug resistance of Psendomonas aeruginosa in ICU during 2006-2007
10.3760/cma.j.issn.1673-4130.2009.05.008
- VernacularTitle:2006与2007年ICU病房铜绿假单胞菌耐药性分析
- Author:
Xiuwen LI
;
Yihua ZHANG
;
Yi LIU
- Publication Type:Journal Article
- Keywords:
Intensive care units;
Pseudomonas aeruginosa;
Drug resistance,bacterial
- From:
International Journal of Laboratory Medicine
2009;30(5):439-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the drug resistance and the vicissitude of Pseudomonas aerugi-nosa in Intensive Care Unit (ICU), in order to provide basis for rational use of antibiotics in clinic. Methods Identification of bacteria was performed by applying ATB Expression Identification System produced by BioMerieux Company; drug susceptibility tesr was done by using K-B method. The drug resistance of Pseudomonas aeruginosa was compared between ICU and general wards; and then the difference of drug resistance was investigated between 2006 and 2007. Resnlts The more sensitive an-tibiotics to Pseudomonas aeruginosa in ICU of our hospital were as follows, amikacin (resistance rate 6.7%-9.4%), eiprofloxacin (resistance rate 7.7%-24.7%), cefoperazone/sulbactam (resistance rate 11.5%-34%), ceftazidime (resistance rate 11.5%-37.7%), aztreonam (resistance rate 20.2%-40.6%). The drug resistance rate of ICU was higher than that of the general wards, and the drug re-sistance rates to ciprofloxacin, ceftazidime, cefoperazone/sutbaetam,meropenem, imipenem and aztreo-nam in 2007 were significantly higher than those in 2006 (P<0.01). Conclusion The drug resistance rate of Pseudomonas aeruginosa in ICU of our hospital was very high,and it is rising year by year. So it is important to retrospect the results of the drug resistance periodically and provide the up-to-the-mi-nute data of epidemiology and vicissitude of drug resistance.
